Genipin is a dye biocompound that is 100% natural, and has been used widely in medical and food technology. And considered safest than many other options of other chemicals. While its safe for majority of people, several individuals may have allergic reaction to genipin. Especially people with history of plant-based food allergy or skincare ingredients allergy. It is advised for skin sensitive individuals to do small patch test by appliying small cuts of tattoo before applying the whole tattoo